What symptom is commonly experienced by patients taking niacin?

Patients taking niacin commonly experience postdose flushing as a side effect. This flushing occurs due to the release of prostaglandins, which are compounds that cause blood vessels to widen, leading to increased blood flow to the skin. This reaction can manifest as a warming sensation and reddening of the skin, especially in areas like the face and neck. This symptom is generally transient and may occur shortly after the medication is taken.

Understanding this side effect is important because it helps patients manage their expectations when starting niacin therapy. It may also inform decisions about dosage adjustments or pre-medication strategies to mitigate flushing. Other side effects like bronchospasm, hypotension, or increased appetite are less commonly associated with niacin therapy, making flushing a more prevalent and expected symptom. Recognizing this can aid healthcare providers in patient education and in addressing any concerns that patients may have when initiating treatment.