What is a common side effect of long-term corticosteroid use in older adults?

Long-term corticosteroid use in older adults is notably associated with weight gain due to several physiological mechanisms. Corticosteroids induce a state of increased gluconeogenesis, leading to elevated blood sugar levels which can result in fat redistribution and an increase in body weight. Additionally, they can stimulate appetite, further contributing to weight gain. This specific effect is particularly significant in geriatric populations, who may already be dealing with other weight-related health issues.

Understanding the side effects of corticosteroids is critical for managing long-term treatment plans, especially as older adults might have coexisting conditions such as diabetes or hypertension, which can be exacerbated by weight gain. It's also essential to monitor weight regularly as part of comprehensive care in the geriatric population using corticosteroids, to mitigate potential health risks associated with weight increase.